Arizona Diamondbacks at San Francisco Giants odds, picks and predictions

Jess Root
Staff Writer

The Arizona Diamondbacks (9-11) and San Francisco Giants (9-11) play the 2nd game of a 4-game series Friday. First pitch from Oracle Park is at 10:15 p.m. ET (Apple TV+). Let's analyze BetMGM Sportsbook's lines around the Diamondbacks vs. Giantsodds and make our expert MLB picks and predictions for the best bets.

Season series: Giants lead 1-0

The Diamondbacks have lost 2 straight and 3 of their last 4. They opened the series with a 5-0 loss Thursday as starting RHP Ryne Nelson was forced to leave in the 2nd inning after getting hit by a line drive on his pitching arm. It was the 1st time they were shut out this season.

The Giants have won back-to-back games for the 2nd time this season. They have won 3 of their last 4 games.

Diamondbacks at Giants projected starters

LHP Jordan Montgomery vs. LHP Blake Snell

Montgomery (10-11, 3.20 ERA in 2023) makes his 2024 debut. He had a 1.19 WHIP, 2.3 BB/9 and 7.9 K/9 through 188 2/3 IP in 32 starts last season with the St. Louis Cardinals and Texas Rangers.

  • Went 3-1 with a 2.90 ERA in 5 postseason appearances last year for the World Series champion Rangers
  • 0-2 with a 2.19 ERA in 2 career starts vs. Giants

Snell (0-2, 12.86 ERA) makes his 3rd start. He has a 1.86 WHIP, 4 BB and 9 K in 7 innings.

  • Last start: Loss, 4 IP, 7 ER, 6 H, 2 BB, 4 K in 9-4 road loss to Tampa Bay Rays Sunday
  • 5-1 with a 1.11 ERA in 8 career starts vs. Arizona

Win your fantasy baseball league with BaseballHQ.com. For decades, BHQ has been helping players just like you win! BHQ offers Draft Prep and full-season subscriptions. Sign up today and start winning!

Diamondbacks at Giants odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:45 a.m. ET.

  • Moneyline (ML): Diamondbacks +110 (bet $100 to win $110) | Giants -130 (bet $130 to win $100)
  • Run line (RL)/Against the spread (ATS): Diamondbacks +1.5 (-190) | Giants -1.5 (+155)
  • Over/Under (O/U): 7.5 (O: -110 | U: -110)

Diamondbacks at Giants picks and predictions

Prediction

Giants 4, Diamondbacks 3

Moneyline

Arizona (+110) has been waiting for the debut of Montgomery, as LHP Eduardo Rodriguez was placed on the 60-day IL.

But the issue for Arizona has mostly been the back end of the bullpen while closer Paul Sewald has been out. It has already blown 5 save opportunities in 20 games.

Snell has struggled early on but has been nearly perfect in his career against Arizona.

Montgomery probably won't go deep into the game in his debut, so Arizona will need to rely on the bullpen.

BET GIANTS (-130).

Run line/Against the spread

Three of the Giants' last 7 wins have been by only 1 run. The Diamondbacks have four 1-run losses this season.

Betting the D'Backs to cover +1.5 at -190 isn't a good bet, but with Snell's struggles early this season, despite his career numbers against Arizona, this feels like a game where Arizona has a lead from a strong Montgomery debut, only to have the bullpen fail.

PASS.

Over/Under

Both of Snell's starts this season have had 9 or more total runs.

Five of Arizona's last 6 games have not reached 9 total runs.

The Giants' last 2 games have not reached 9 total runs, but 3 of their last 6 have.

Seven of the last 8 meetings have not reached 9 runs.

BET UNDER 8 (-110).

Play our free daily Pick’em Challenge and win! Play now!

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow Jess Root on Twitter/X. Follow SportsbookWire on Twitter/X andlike us on Facebook.

Additional MLB coverage:

BaseballHQ Fantasy Baseball